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• 基金项目：

• 邓承宗
• 中山医学院肿瘤研究所

• 区宝祥
• 中山医学院肿瘤研究所

• 黄家琛
• 中山医学院肿瘤研究所

• 卓子兰
• 中山医学院肿瘤研究所

• 冼汉隆
• 中山医学院化学教研室

• 姚铭琛
• 中山医学院化学教研室

• 陈妙英
• 中山医学院化学教研室

• 李增禧
• 广东省测试分析研究所

• 盛少禹
• 广东省测试分析研究所

• 叶子枫
• 广东省测试分析研究所

• 摘要：本文共检查了34名电镀厂生产工人和10名该厂行政人员的外用淋巴细胞姐妹染色单体交换,结果表明,两者间有显著性的差异(P<0.01).但不同工龄间的差异并不明显.还分析了其中7名镀镍工人和7名镀铬工人以及三名已调离生产车间的电镀工人外周淋巴细胞染色体畸变.结果表明均有明显增加.此外还对镀镍和镀铬工人头发和粪便中镍、铬含量以及他们所在车间空气中镍、铬含量进行了测定.

• Abstract：A group of 34 electroplating workers occupationally exposed to nickel or chromium and a control group of 10 were examined for sister-chromatid exchanges in their peripheral lymphocytes. Frequency of SCEs was significantly higher in cells of electroplating worker in comparision with controls. The level of significance was P<0.01, according to the t-test. Differences of the frequencies of SCEs between the age groups were not obvious.Out of the 34 electroplating workers, 7 workers occupationally exposed to nickel and T to chromium, not only the frequency of SCEs was examined, but also chromosomal aberrations. The results showed that the chromosomal aberrations of the workers occupationally exposed to nickel and to chromium were higher than the controls.Also, nickel and chromium "concentrations in "air of the electroplating workshop, as well as contents of nickel and chromium in hair and feces of the workers were determined,

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