研究论文
王孝萱,范占如,张宇撰,郑荣梁.兰州地区空气飘尘对人淋巴细胞SCE的诱发及DNA的损伤[J].环境科学学报,1989,9(3):352-355
兰州地区空气飘尘对人淋巴细胞SCE的诱发及DNA的损伤
- SISTER CHROMATID EXCHANGE AND DNA DAMAGE IN HUMAN LYMPHOCYTES INDUCED BY AIR DUST IN LANZHOU AREA
- 基金项目：国家自然科学基金资助项目
- 作者
- 单位
- 王孝萱
- 兰州大学生物物理研究室
- 范占如
- 兰州大学生物物理研究室
- 张宇撰
- 兰州大学生物物理研究室
- 郑荣梁
- 兰州大学生物物理研究室
- 摘要：用苯、己烷、异丙醇(7:2:1)混合溶剂萃取兰州市石油化工区及离市区西64公里农村的空气飘尘.萃取物能使人淋巴细胞姊妹染色单体互换频率(SCE)增高,使SCE比对照组增高一倍的浓度:化工区为23μg/ml、农村为47μg/ml,萃取物还能损伤DNA棋板,证明化工区空气飘尘的致突变或致癌的机率比农村大.
- Abstract：The air dust collected from petroleum chemical industrial region in Lanzhou and rural area 64 km from the. city were extracted by mixed solvent of benzene, hexane and isopropanol (7:2:1) for 8 hours. The sister chromatid exchange (SCE) frequency was increased by all extracts and the double SCE frequency concentration of extract from air dust in the extraction system was 23 μg/ml and 47 μg/ml for samples from industrial and rural areas respectively. The extracts were found to be able to damage the DNA template as well.
摘要点击次数： 1700 全文下载次数： 2338
