研究报告
李辉,陈瑀,封梦娟,王博,卜元卿,张圣虎.南京市饮用水源地抗生素污染特征及风险评估[J].环境科学学报,2020,40(4):1269-1277
南京市饮用水源地抗生素污染特征及风险评估
- Pollution characteristics and risk assessment of antibiotics in Nanjing drinking water sources
- 基金项目：国家重点研发计划项目（No.2017YFD0800705）
- 作者
- 单位
- 李辉
- 北京百灵天地环保科技股份有限公司, 北京 100045
- 陈瑀
- 1. 生态环境部南京环境科学研究院, 南京 210042;2. 贵州大学资源与环境工程学院, 贵阳 550025
- 封梦娟
- 1. 生态环境部南京环境科学研究院, 南京 210042;2. 中国药科大学工学院, 南京 211198
- 王博
- 生态环境部南京环境科学研究院, 南京 210042
- 卜元卿
- 生态环境部南京环境科学研究院, 南京 210042
- 张圣虎
- 生态环境部南京环境科学研究院, 南京 210042
- 摘要：采用固相萃取-液相色谱-串联质谱技术（SPE-HPLC-MS/MS），对南京市饮用水源地抗生素含量及分布特征进行了分析.结果表明，17个采样点总浓度为0.56~1994.96 ng·L-1，共检出5种大环内酯类、13种磺胺类、3种四环素类、8种喹诺酮类抗生素，平均浓度为0.30~37.07 ng·L-1，其中检出浓度最高的抗生素为环丙沙星（CIP），浓度为317.60 ng·L-1，检出率最高的抗生素为克林霉素（CLI），检出率为88.24%.与国内部分河流相比，南京市饮用水源地水体中大环内酯类、四环素类、喹诺酮类抗生素残留浓度处于较高水平.生态风险评估结果表明，点位S7具有最高的联合风险熵值（24.58），氧氟沙星（OFX）的风险熵值最高，达到13.06；健康风险评估结果表明，9种抗生素对人体健康的风险熵QH为1.70×10-3~9.47，强力霉素（DOX）、诺氟沙星（NOR）、恩诺沙星（ERX）、CIP和OFX对大部分年龄段的人体健康具有高水平风险.
- Abstract：The pollution characteristics of antibiotics in water source of Najing were analyzed by using the solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry (SPE-HPLC-MS/MS).The result showed that the total detected concentration of 17 sampling points ranged from 0.56 to 1994.96 ng·L-1, and five macrolides, thirteen sulfonamides, three tetracycline, eight fluoroquinolones were detected with average concentration ranged from 0.30 ng·L-1 to 37.07 ng·L-1, including ciprofloxacin(CIP) with the highest concentration of 317.60 ng·L-1 and clindamycin(CLI) with the highest detection of 88.24%. Compared with some rivers in China, the macrolides, tetracyclines and fluoroquinolones antibiotics in the Nanjing Drinking water sources are at a relatively high level. The risk assessment results show that the largest cumulative risk of S7 is 24.58, and the highest risk quotient of ofloxacin(OFX) is 13.06; the health risk quotients of nine antibiotics range from 1.70×10-3 to 9.47, and doxycycline (DOX), norfloxacin (NOR), enrofloxacin (ERX), CIP and OFX have a high level of health risk for most age groups.
- Key words：antibiotics source of drinking water Nanjing reach of the Yangtze River ecological risk health risks
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