叶伟鹏,刘苗苗,毕军.中国臭氧短期暴露与人群死亡之间关系的Meta分析研究[J].环境科学学报,2020,40(7):2644-2651
中国臭氧短期暴露与人群死亡之间关系的Meta分析研究
- Meta-analysis of the associations between short-term ozone exposure and human mortality in China
- 基金项目：江苏省自然科学基金（No.BK20180350）
- 叶伟鹏
- 南京大学环境学院, 污染控制与资源化研究国家重点实验室, 南京 210023
- 刘苗苗
- 南京大学环境学院, 污染控制与资源化研究国家重点实验室, 南京 210023
- 毕军
- 南京大学环境学院, 污染控制与资源化研究国家重点实验室, 南京 210023
- 摘要：为探讨中国臭氧短期暴露与死亡率之间的关系，更新适用于中国本地化的暴露-反应系数，本研究全面检索了1990年1月1日-2020年1月1日在Web of Science数据库、PubMed、中国期刊全文数据库（CNKI）、万方医学数据库和维普数据库上发表的文献，以"O3/臭氧（ozone）"、"空气污染（air pollution）"、"死亡率（mortality）"、"时间序列（time-series）"，"病例交叉（case-crossover）"、"中国（China）"为关键词，对符合纳入标准的文献进行质量评价后提取相关数据，通过Meta分析方法合并估计值.结果显示，大气中臭氧浓度每增加10 μg·m-3，人群总死亡率、心血管系统疾病和呼吸系统疾病死亡率分别增加0.40%（95% CI：0.28%~0.52%）、0.67%（95% CI：0.46%~0.88%）、0.23%（95% CI：-0.20%~0.66%）.亚组分析结果表明，除季节外，温度、年龄、性别均不存在显著的修饰作用.本文结论可为开展城市大气污染健康风险精细化评估提供依据.
- Abstract：To update the associations between short-term ozone exposure and mortality applicable to China, this study search web of science database, PubMed, China journal full text database (CNKI), Wanfang medical database and VIP database published from 1 January 1990 to 1 January 2020, with key words "O3" or "ozone", "air pollution", "mortality", "time-series" or "case-crossover", "China" and their Chinese expression, and after the quality evaluation, extract the relevant data from selected literatures that meet the inclusion criteria. Based on extracted data, this study further combine the estimated values of exposure response coefficients using meta-analysis approach. The results show that for per 10 μg·m-3 increase in ozone concentration, total mortality, cardiovascular disease mortality and respiratory disease mortality increase by 0.40%(95%CI:0.28%~0.52%), 0.67%(95%CI:0.46%~0.88%) and 0.23%(95%CI:-0.20%~0.66%), respectively. Subgroup analysis show that except for season, temperature, age and gender have no significant modification. The findings of this study provide a basis for refined health risk assessment of urban air pollution in China.
