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研究报告

张玲,白军红,梁金凤,王亚琪,魏卓群,杜书栋.基于CiteSpace文献计量的湖泊抗生素抗性基因研究进展与热点分析[J].环境科学学报,2022,42(1):308-320

Research progress and hot spot analysis of antibiotic resistance genes in lakes based on CiteSpace literature metrology

摘要：以Web of Science数据库及CNKI（中国知网）的文献资料为数据源，利用CiteSpace文献计量工具，对湖泊抗生素抗性基因的研究文献从发展路径、主题演变以及研究热点等方面进行剖析，以此探讨国内外该领域的研究现状、热点和发展态势.结果表明，湖泊中抗生素抗性基因的研究文献发文数量和载文期刊数量呈快速增长态势；我国在文献发文数量、论文被引频次方面占据重要地位，有着较强的国际学术影响力.从关键词聚类分析表明湖泊抗生素抗性基因研究已经从Bacteria、 Antibiotic Resistance、Surface Water、抗生素抗性细菌和抗性基因等内容延伸到ARGs源解析、淡水环境和检测技术等相关方向；从突现词分析可知，微生物群落对抗生素抗性基因的响应和机理、潜在的人体健康风险评价和量化以及抗生素抗性基因与关键影响因素的识别是未来该研究领域的重要方向和热点内容.

Abstract：The literature in the research field of lake antibiotic resistance genes （ARGs）， in terms of development path， theme evolution and research hotspots， is analyzed to review the current situation， future development trends and research hotspots at home and abroad， by using CiteSpace software and Web of Science and CNKI （China National Knowledge Infrastructure） as data sources. Results showed the number of publications and journals concerning the study of ARGs in lakes is increasing rapidly， and China occupied an important position in the number of publications and citation frequency， as well as had a strong academic influence internationally. Keyword cluster analysis showed that the research of lake ARGs had been extended with “antibiotic resistance” and “abundance of bacteria”， “antibiotic resistance bacteria” and “resistance genes in surface water”， to the source analysis of ARGs in the freshwater environment and novel detection technology. From the analysis of burst terms， it can be seen that the response and mechanism of microbial communities to ARGs， the evaluation and quantification of potential human health risks， the identification of ARGs and key influencing factors are the important directions and hot topics in the future.