工业废水处理厂中抗性基因与微生物群落的分布特征及其两者之间的相关性
- Distribution characteristics of antibiotic resistance genes and microbial communities in industrial wastewater treatment plants and correlation analysis of both
- 基金项目：国家自然科学(No.52100104与52170053)、西安理工大学博士留学联合培养基金(No. 104-252092301)和陕西省科技创新领军计划(No. .2023GXLH-047)
- 摘要：工业废水处理厂（industrial wastewater treatment plants，IWWTPs）作为高浓度多种类污染物汇集的场所，其具有极大的诱导抗生素抗性基因（antibiotic resistance genes, ARGs）形成、增殖与传播的潜能。了解ARGs在其全流程处理过程中的分布对于控制其扩散非常重要。在此工作中，我们从选定的典型IWWTP沿程的处理单元收集废水样本，包括缺氧-好氧(Anoxic-Oxic，A/O)、臭氧高级氧化和氯消毒单元，并考虑季节（温度）变化，分析了相应的ARGs和微生物群落结构信息。结果表明，宿主细菌的进化与ARGs高度相关，也就是说，宿主细菌是引起ARGs变化的决定性因素。
- Abstract：Industrial wastewater treatment plants (IWWTPs) present great potential inducing the formation, proliferation and spread of antibiotic resistance genes (ARGs) due to the stimulation of high content and complicated pollutants on bacteria. Understanding the distribution of ARGs along the treatment train is of high importance for controlling their spreading. In the present work, wastewater samples were collected from treatment units along a typical IWWTP including, anoxic-oxic (A/O), ozone oxidation and chlorine disinfection units. Corresponding ARGs and microbial community structure were analyzed, considering seasonal (temperature) variation. The results show that the evolution of host bacteria and ARGs are highly related, that is, the host bacteria are the decisive factor inducing the changes of ARGs.
